Biological indicators (BIs) provide information on whether necessary conditions were met to kill a specified number of microorganisms (bacterial spores) for a given sterilization process. Geobacillus stearothermophilus spores are primarily used in steam and vaporized hydrogen peroxide (VHP) biological indicators due to their high resistance to these sterilization processes.
BIs are typically used within process challenge devices (PCD), designed to represent the most challenging products routinely processed. A passing result for the BI within the PCD demonstrates that the sterilization cycle was effective at inactivating the BI, providing Sterile Processing Department staff with a level of assurance in their sterilization process.
STERIS biological indicators are designed for use in steam or VHP sterilization processes. From self-contained biological indicators (SCBI) to challenge packs or test packs, these devices play a critical role in sterility assurance and provide the only direct measure of the lethality of the sterilization process.
* As of 12/29/2017 the Celerity 20 HP Biological Indicator has been validated for use in all cycles on the STERRAD 100NX, STERRAD NX and STERRAD 100S Sterilizers.
1 STERRAD® IS THE REGISTERED TRADEMARK OF Advanced Sterilization Products, Division of Ethicon Inc., a Johnson & Johnson Company.