Liquid Chemical Sterilization

When compared to high level disinfection (HLD), liquid chemical sterilization (LCS) provides a higher level of reprocessing assurance for heat-sensitive critical and semi-critical medical devices.

The SYSTEM 1E® Liquid Chemical Sterilant Processing System provides safe and effective reprocessing of heat-sensitive, critical and semi-critical devices, and is the only practical solution for low temperature sterilization of heat-sensitive, complex endoscopes, including flexible multi-channel devices such as duodenoscopes used in endoscopic retrograde cholangiopancreatography (ERCP) procedures.

Liquid chemical sterilization Categories

Liquid Chemical Sterilization

system® 1e liquid chemical sterilant processing system

SYSTEM 1E  Liquid Chemical Sterilant Processing System

  • For reprocessing of cleaned, reusable heat-sensitive critical and semi-critical devices
  • Kills all spores during exposure in the standard cycle
  • The only practical low temperature sterilization solution for heat-sensitive complex flexible endoscopes, such as duodenoscopes
  • Rapid 23 minute cycle time

SYSTEM® 1E resources

Effectiveness of the SYSTEM 1E Liquid Chemical Sterilant Processing System for reprocessing duodenoscopes1

SYSTEM 1E® Liquid Chemical Sterilant Processing System for Processing Duodenoscopes2

Technical Data Monograph

SYSTEM 1E Site Prep & Installation Guide

FDA Clearance Letter

510 (k) Summary

1 American Journal of Infection Control (2016)

2 On behalf of the authors, STERIS is posting this abstract of the research paper "Effectiveness of the SYSTEM 1E Liquid Chemical Sterilant Processing System for Processing Duodenoscopes." The full manuscript has been accepted for publication.

Steriliant Accessories and Record Keeping

S40 Sterilant

S40 Sterilant concentrate

  • Designed for use in the SYSTEM 1E Processor
  • Single-use peracetic acid chemistry
  • Eliminates all microbial life, including bacterial endospores
  • Non-fixative oxidative chemistry

verify spore test strip
for S40 sterilant

VERIFY Spore Test Strip for S40 Sterilant

  • Designed for use with S40 Sterilant
  • Tests sporicidal activity of the S40 Sterilant
  • Fast, 24 hour incubation time

verify chemical indicator
for system 1e

VERIFY chemical indicator for system 1e

  • Designed for use with the SYSTEM 1E Processor
  • Verifies the minimum recommended concentration of S40 Sterilant use dilution is met to achieve liquid chemical sterilization

system 1e®
record keeping

SYSTEM 1E Record Keeping

  • Cycle log forms and envelopes
  • Assists with compliance to ANSI/AAMI ST58:2005/(R) documentation requirements

Device Compatibility and Education

system 1e® device
compatibility matrix

SYSTEM 1E device compatibility matrix

  • Confirm that your medical devices and accessories are compatible for processing with SYSTEM 1E


steris university

STERIS University

  • Education and Training
  • Earn Free CEs
STERIS Corporation

STERIS is a leading provider of infection prevention
and other procedural products and services.

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