ASCENDO™ Submucosal Lifting Agent

Product Overview

The ASCENDO™ submucosal lifting agent is intended for use in gastrointestinal endoscopic procedures. Endoscopic lifting agents are used for the submucosal lift of polyps, adenomas, early-stage cancers, or other gastrointestinal (GI) mucosal lesions prior to excision with a snare or endoscopic device.

HOW THE ASCENDO LIFTING AGENT WORKS

The effective removal of lesions during an endoscopic resection can be challenging and time-consuming. An endoscopic lifting agent is delivered by an injection needle advanced through the working channel of the endoscope. It helps to provide differentiation between the muscle layer and submucosa, reducing the risk of perforation when endoscopic mucosal resection (EMR) is performed. Additionally, the blue coloring customary to gastrointestinal lesion lifting agents allows for delineation of the lesion margin compared to healthy tissue, thus supporting complete resection. Using a submucosal lifting agent can save physicians time by supporting quick localization of the separation of the polyp from the muscle wall as well as reducing risks like perforation.

The ASCENDO lifting agent is designed to provide a submucosal cushion of optimal height and duration, allowing the endoscopist an easy and safe resection procedure. The submucosal lifting agent acts as a colored translucent solution to help to clarify the area where it is injected. This helps to assist the endoscopist in visualizing the margins of the target lesion and performing the resection procedure, thereby decreasing the risk of damaging the external muscular layer, which could lead to perforation. The GI lifting agent is injected into the submucosa, beneath the lesion to be excised.

The ASCENDO submucosal lifting agent is a solution used for the submucosal lift of polyps, adenomas, early-stage cancers, or other gastrointestinal mucosal lesions prior to excision with a snare or endoscopic device in gastrointestinal endoscopic procedures. Consisting of sodium hyaluronate, Methylene Blue, and normal saline, this lifting agent is supplied in a ready-to-use, prefilled syringe containing 5 ml of the agent.

WHY THE ASCENDO LIFTING AGENT

• Quality Endoscopic Lift – Helps to clarify the area for visualizing the margins of the target lesion and performing the resection procedure and is designed to provide a submucosal cushion of optimal height and duration, allowing the endoscopist an easy and safe resection procedure
• Prefilled Syringe – Preparation is simplified with a ready-to-use product design
• Biocompatible – Consists of sodium hyaluronate, commonly referred to as hyaluronic acid, a biopolymer naturally present in the human body
• Sterile – A single-use, sterile submucosal lifting agent for GI lesions and polyps

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